You Need To Know! ‘Grey’s Anatomy’ Season 21: Cast Changes, Premiere Date & More Details!

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You Need To Know! ‘Grey’s Anatomy’ Season 21: Cast Changes, Premiere Date & More Details!

2026/09/23 Report

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Returning to Grey Sloan Memorial

As we gear up for the highly anticipated 21st season of "Grey's Anatomy," there are significant changes and updates that every fan should be aware of. The series, known for its dramatic twists and emotional storylines, is set to continue its legacy with some familiar faces and new developments.

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Premiere Date Announced

Mark your calendars! "Grey's Anatomy" Season 21 will premiere on Thursday, September 26, 2024, at 10 PM ET. This time slot marks a shift from its usual 9 PM slot, accommodating the new medical drama "Doctor Odyssey" preceding it.

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