The article provides information on how long it takes to cook a 20-pound turkey, whether it is thawed or stuffed. A thawed 20-pound turkey takes around 4 hours and 15 minutes to 4 hours and 30 minutes to cook at 325 degrees Fahrenheit. It is important to use a meat thermometer to ensure the breast meat reaches a minimum temperature of 165 degrees Fahrenheit and the dark meat reaches 175 degrees Fahrenheit.
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