Sam and Dean, the beloved Winchester brothers on the hit show Supernatural, are known for their epic pranks on each other throughout the series. These pranks often serve as moments of comic relief amidst the intense and dark storylines.
One of the earliest pranks that Sam and Dean engage in is the classic hallucination prank. In Season 2, Sam slips some supernatural drugs into Dean's drink, causing him to experience terrifying hallucinations.
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