After a cliffhanger finale that left fans gasping, Grey’s Anatomy is set to return for its 22nd season on October 9, 2025, at 10 p.m. ET/PT on ABC. The upcoming season promises to delve deeper into the lives of the doctors at Grey Sloan Memorial Hospital, exploring themes of resilience, love, and the complexities of the medical world.
Season 21 concluded with a dramatic hospital explosion, leaving the fates of several beloved characters hanging in the balance.
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