General Hospital isn’t just the longest-running American soap still on TV—it’s also been a launchpad (or a fascinating pitstop) for stars you’d never guess walked the halls of Port Charles. From Oscar nominees to reality show royalty, these celebrity cameos tell a hidden Hollywood story worth retelling.
Before he melted hearts as Uncle Jesse on Full House, John Stamos played Blackie Parrish, a troubled teen turned rock star, on General Hospital from 1982 to 1984.
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